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UNC Drug Discovery Initiative

 

The UNC Drug Discovery Initiative takes drug discovery and development at UNC further than ever before, offering health science researchers additional tools to identify and screen targets, and help to advance therapies to patients. The Drug Discovery Initiative is powered by Eshelman Innovation in a collaboration with the UNC School of Medicine, the Lineberger Comprehensive Cancer Center, the Eshelman School of Pharmacy, and UNC Research.

 

CRISPR Screening Facility

CRISPR SCREENING FACILITY

 

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DNA

DNA ENCODED LIBRARY

 

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Current and Future Capabilities

Novel Target Identification

  • UNC CRISPR Genetic and Epigenetic Screening Center (Opening Q3 ’21)

 

Target Screening

  • Small Molecule: DNA-Encoded Libraries (DEL)
    • Collaboration with HitGen
  • Antibody Screening

 

Translational Research/ Asset Development

  • On-Campus Capabilities
    • Small Molecule
    • Cell/Gene Therapies
  • CRO/External Partnerships
    • Small Molecules
    • Antibodies/Biologics
    • mRNA Technologies